diff --git a/django/db/models/sql/query.py b/django/db/models/sql/query.py
index 5100869b34..b3f130c0b4 100644
--- a/django/db/models/sql/query.py
+++ b/django/db/models/sql/query.py
@@ -696,6 +696,7 @@ class Query(BaseExpression):
         # except if the alias is the base table since it must be present in the
         # query on both sides.
         initial_alias = self.get_initial_alias()
+        rhs = rhs.clone()
         rhs.bump_prefix(self, exclude={initial_alias})
 
         # Work out how to relabel the rhs aliases, if necessary.
diff --git a/tests/queries/tests.py b/tests/queries/tests.py
index 48d610bb2b..7ac8a65d42 100644
--- a/tests/queries/tests.py
+++ b/tests/queries/tests.py
@@ -1357,6 +1357,24 @@ class Queries1Tests(TestCase):
         )
         self.assertSequenceEqual(Note.objects.exclude(negate=True), [self.n3])
 
+    def test_combining_does_not_mutate(self):
+        all_authors = Author.objects.all()
+        authors_with_report = Author.objects.filter(
+            Exists(Report.objects.filter(creator__pk=OuterRef("id")))
+        )
+        authors_without_report = all_authors.exclude(pk__in=authors_with_report)
+        items_before = Item.objects.filter(creator__in=authors_without_report)
+        self.assertCountEqual(items_before, [self.i2, self.i3, self.i4])
+        # Combining querysets doesn't mutate them.
+        all_authors | authors_with_report
+        all_authors & authors_with_report
+
+        authors_without_report = all_authors.exclude(pk__in=authors_with_report)
+        items_after = Item.objects.filter(creator__in=authors_without_report)
+
+        self.assertCountEqual(items_after, [self.i2, self.i3, self.i4])
+        self.assertCountEqual(items_before, items_after)
+
 
 class Queries2Tests(TestCase):
     @classmethod