diff --git a/django/contrib/postgres/search.py b/django/contrib/postgres/search.py
index 4ab27605cb..52e925d27a 100644
--- a/django/contrib/postgres/search.py
+++ b/django/contrib/postgres/search.py
@@ -1,3 +1,4 @@
+from django.db.backends.postgresql.psycopg_any import is_psycopg3
 from django.db.models import (
     CharField,
     Expression,
@@ -10,9 +11,45 @@ from django.db.models import (
 )
 from django.db.models.expressions import CombinedExpression, register_combinable_fields
 from django.db.models.functions import Cast, Coalesce
+from django.utils.regex_helper import _lazy_re_compile
 
 from .utils import CheckPostgresInstalledMixin
 
+if is_psycopg3:
+    from psycopg.adapt import Dumper
+
+    class UTF8Dumper(Dumper):
+        def dump(self, obj):
+            return bytes(obj, "utf-8")
+
+    def quote_lexeme(value):
+        return UTF8Dumper(str).quote(psql_escape(value)).decode()
+
+else:
+    from psycopg2.extensions import adapt
+
+    def quote_lexeme(value):
+        adapter = adapt(psql_escape(value))
+        adapter.encoding = "utf-8"
+        return adapter.getquoted().decode()
+
+
+spec_chars_re = _lazy_re_compile(r"['\0\[\]()|&:*!@<>\\]")
+multiple_spaces_re = _lazy_re_compile(r"\s{2,}")
+
+
+def normalize_spaces(val):
+    """Convert multiple spaces to single and strip from both sides."""
+    if not (val := val.strip()):
+        return None
+    return multiple_spaces_re.sub(" ", val)
+
+
+def psql_escape(query):
+    """Replace chars not fit for use in search queries with a single space."""
+    query = spec_chars_re.sub(" ", query)
+    return normalize_spaces(query)
+
 
 class SearchVectorExact(Lookup):
     lookup_name = "exact"
@@ -205,6 +242,9 @@ class SearchQuery(SearchQueryCombinable, Func):
         invert=False,
         search_type="plain",
     ):
+        if isinstance(value, LexemeCombinable):
+            search_type = "raw"
+
         self.function = self.SEARCH_TYPES.get(search_type)
         if self.function is None:
             raise ValueError("Unknown search_type argument '%s'." % search_type)
@@ -383,3 +423,104 @@ class TrigramWordSimilarity(TrigramWordBase):
 
 class TrigramStrictWordSimilarity(TrigramWordBase):
     function = "STRICT_WORD_SIMILARITY"
+
+
+class LexemeCombinable:
+    BITAND = "&"
+    BITOR = "|"
+
+    def _combine(self, other, connector, reversed):
+        if not isinstance(other, LexemeCombinable):
+            raise TypeError(
+                "A Lexeme can only be combined with another Lexeme, "
+                f"got {other.__class__.__name__}."
+            )
+        if reversed:
+            return CombinedLexeme(other, connector, self)
+        return CombinedLexeme(self, connector, other)
+
+    # On Combinable, these are not implemented to reduce confusion with Q. In
+    # this case we are actually (ab)using them to do logical combination so
+    # it's consistent with other usage in Django.
+    def __or__(self, other):
+        return self._combine(other, self.BITOR, False)
+
+    def __ror__(self, other):
+        return self._combine(other, self.BITOR, True)
+
+    def __and__(self, other):
+        return self._combine(other, self.BITAND, False)
+
+    def __rand__(self, other):
+        return self._combine(other, self.BITAND, True)
+
+
+class Lexeme(LexemeCombinable, Value):
+    _output_field = SearchQueryField()
+
+    def __init__(
+        self, value, output_field=None, *, invert=False, prefix=False, weight=None
+    ):
+        if value == "":
+            raise ValueError("Lexeme value cannot be empty.")
+
+        if not isinstance(value, str):
+            raise TypeError(
+                f"Lexeme value must be a string, got {value.__class__.__name__}."
+            )
+
+        if weight is not None and (
+            not isinstance(weight, str) or weight.lower() not in {"a", "b", "c", "d"}
+        ):
+            raise ValueError(
+                f"Weight must be one of 'A', 'B', 'C', and 'D', got {weight!r}."
+            )
+
+        self.prefix = prefix
+        self.invert = invert
+        self.weight = weight
+        super().__init__(value, output_field=output_field)
+
+    def as_sql(self, compiler, connection):
+        param = quote_lexeme(self.value)
+        label = ""
+        if self.prefix:
+            label += "*"
+        if self.weight:
+            label += self.weight
+
+        if label:
+            param = f"{param}:{label}"
+        if self.invert:
+            param = f"!{param}"
+
+        return "%s", (param,)
+
+    def __invert__(self):
+        cloned = self.copy()
+        cloned.invert = not self.invert
+        return cloned
+
+
+class CombinedLexeme(LexemeCombinable, CombinedExpression):
+    _output_field = SearchQueryField()
+
+    def as_sql(self, compiler, connection):
+        value_params = []
+        lsql, params = compiler.compile(self.lhs)
+        value_params.extend(params)
+
+        rsql, params = compiler.compile(self.rhs)
+        value_params.extend(params)
+
+        combined_sql = f"({lsql} {self.connector} {rsql})"
+        combined_value = combined_sql % tuple(value_params)
+        return "%s", (combined_value,)
+
+    def __invert__(self):
+        # Apply De Morgan's theorem.
+        cloned = self.copy()
+        cloned.connector = self.BITAND if self.connector == self.BITOR else self.BITOR
+        cloned.lhs = ~self.lhs
+        cloned.rhs = ~self.rhs
+        return cloned
diff --git a/docs/ref/contrib/postgres/search.txt b/docs/ref/contrib/postgres/search.txt
index 4647fcbfa2..88e3cfaeb0 100644
--- a/docs/ref/contrib/postgres/search.txt
+++ b/docs/ref/contrib/postgres/search.txt
@@ -96,7 +96,7 @@ Examples:
 
 .. code-block:: pycon
 
-    >>> from django.contrib.postgres.search import SearchQuery
+    >>> from django.contrib.postgres.search import SearchQuery, Lexeme
     >>> SearchQuery("red tomato")  # two keywords
     >>> SearchQuery("tomato red")  # same results as above
     >>> SearchQuery("red tomato", search_type="phrase")  # a phrase
@@ -105,6 +105,7 @@ Examples:
     >>> SearchQuery(
     ...     "'tomato' ('red' OR 'green')", search_type="websearch"
     ... )  # websearch operators
+    >>> SearchQuery(Lexeme("tomato") & (Lexeme("red") | Lexeme("green")))  # Lexeme objects
 
 ``SearchQuery`` terms can be combined logically to provide more flexibility:
 
@@ -118,6 +119,10 @@ Examples:
 See :ref:`postgresql-fts-search-configuration` for an explanation of the
 ``config`` parameter.
 
+.. versionchanged:: 6.0
+
+    :class:`Lexeme` objects were added.
+
 ``SearchRank``
 ==============
 
@@ -276,6 +281,53 @@ floats to :class:`SearchRank` as ``weights`` in the same order above:
     >>> rank = SearchRank(vector, query, weights=[0.2, 0.4, 0.6, 0.8])
     >>> Entry.objects.annotate(rank=rank).filter(rank__gte=0.3).order_by("-rank")
 
+``Lexeme``
+==========
+
+.. versionadded:: 6.0
+
+.. class:: Lexeme(value, output_field=None, *, invert=False, prefix=False, weight=None)
+
+``Lexeme`` objects allow search operators to be safely used with strings from
+an untrusted source. The content of each lexeme is escaped so that any
+operators that may exist in the string itself will not be interpreted.
+
+You can combine lexemes with other lexemes using the ``&`` and ``|`` operators
+and also negate them with the ``~`` operator. For example:
+
+.. code-block:: pycon
+
+    >>> from django.contrib.postgres.search import SearchQuery, SearchVector, Lexeme
+    >>> vector = SearchVector("body_text", "blog__tagline")
+    >>> Entry.objects.annotate(search=vector).filter(
+    ...     search=SearchQuery(Lexeme("fruit") & Lexeme("dessert"))
+    ... )
+    <QuerySet [<Entry: Apple Crumble Recipes>, <Entry: Banana Split Recipes>]>
+
+.. code-block:: pycon
+
+    >>> Entry.objects.annotate(search=vector).filter(
+    ...     search=SearchQuery(Lexeme("fruit") & Lexeme("dessert") & ~Lexeme("banana"))
+    ... )
+    <QuerySet [<Entry: Apple Crumble Recipes>]>
+
+Lexeme objects also support term weighting and prefixes:
+
+.. code-block:: pycon
+
+    >>> Entry.objects.annotate(search=vector).filter(
+    ...     search=SearchQuery(Lexeme("Pizza") | Lexeme("Cheese"))
+    ... )
+    <QuerySet [<Entry: Cheese on Toast recipes>, <Entry: Pizza recipes>]>
+    >>> Entry.objects.annotate(search=vector).filter(
+    ...     search=SearchQuery(Lexeme("Pizza") | Lexeme("Cheese", weight="A"))
+    ... )
+    <QuerySet [<Entry: Pizza recipes>]>
+    >>> Entry.objects.annotate(search=vector).filter(
+    ...     search=SearchQuery(Lexeme("za", prefix=True))
+    ... )
+    <QuerySet []>
+
 Performance
 ===========
 
diff --git a/docs/releases/6.0.txt b/docs/releases/6.0.txt
index adfac83b8d..fba0935a2b 100644
--- a/docs/releases/6.0.txt
+++ b/docs/releases/6.0.txt
@@ -171,6 +171,12 @@ Minor features
 :mod:`django.contrib.postgres`
 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 
+* The new :class:`Lexeme <django.contrib.postgres.search.Lexeme>` expression
+  for full text search provides fine-grained control over search terms.
+  ``Lexeme`` objects automatically escape their input and support logical
+  combination operators (``&``, ``|``, ``~``), prefix matching, and term
+  weighting.
+
 * Model fields, indexes, and constraints from :mod:`django.contrib.postgres`
   now include system checks to verify that ``django.contrib.postgres`` is an
   installed app.
diff --git a/tests/postgres_tests/test_search.py b/tests/postgres_tests/test_search.py
index a7118e7c79..c206c69747 100644
--- a/tests/postgres_tests/test_search.py
+++ b/tests/postgres_tests/test_search.py
@@ -6,6 +6,7 @@ All text copyright Python (Monty) Pictures. Thanks to sacred-texts.com for the
 transcript.
 """
 
+from django.db import connection
 from django.db.models import F, Value
 
 from . import PostgreSQLSimpleTestCase, PostgreSQLTestCase
@@ -13,11 +14,13 @@ from .models import Character, Line, LineSavedSearch, Scene
 
 try:
     from django.contrib.postgres.search import (
+        Lexeme,
         SearchConfig,
         SearchHeadline,
         SearchQuery,
         SearchRank,
         SearchVector,
+        quote_lexeme,
     )
 except ImportError:
     pass
@@ -769,3 +772,223 @@ class SearchHeadlineTests(GrailTestData, PostgreSQLTestCase):
             "<b>Brave</b>, <b>brave</b>, <b>brave</b>...<br>"
             "<b>brave</b> <b>Sir</b> <b>Robin</b>",
         )
+
+
+class TestLexemes(GrailTestData, PostgreSQLTestCase):
+    def test_and(self):
+        searched = Line.objects.annotate(
+            search=SearchVector("scene__setting", "dialogue"),
+        ).filter(search=SearchQuery(Lexeme("bedemir") & Lexeme("scales")))
+        self.assertSequenceEqual(searched, [self.bedemir0])
+
+    def test_multiple_and(self):
+        searched = Line.objects.annotate(
+            search=SearchVector("scene__setting", "dialogue"),
+        ).filter(
+            search=SearchQuery(
+                Lexeme("bedemir") & Lexeme("scales") & Lexeme("nostrils")
+            )
+        )
+        self.assertSequenceEqual(searched, [])
+
+        searched = Line.objects.annotate(
+            search=SearchVector("scene__setting", "dialogue"),
+        ).filter(search=SearchQuery(Lexeme("shall") & Lexeme("use") & Lexeme("larger")))
+        self.assertSequenceEqual(searched, [self.bedemir0])
+
+    def test_or(self):
+        searched = Line.objects.annotate(search=SearchVector("dialogue")).filter(
+            search=SearchQuery(Lexeme("kneecaps") | Lexeme("nostrils"))
+        )
+        self.assertCountEqual(searched, [self.verse1, self.verse2])
+
+    def test_multiple_or(self):
+        searched = Line.objects.annotate(search=SearchVector("dialogue")).filter(
+            search=SearchQuery(
+                Lexeme("kneecaps") | Lexeme("nostrils") | Lexeme("Sir Robin")
+            )
+        )
+        self.assertCountEqual(searched, [self.verse1, self.verse2, self.verse0])
+
+    def test_advanced(self):
+        """
+        Combination of & and |
+        This is mainly helpful for checking the test_advanced_invert below
+        """
+        searched = Line.objects.annotate(search=SearchVector("dialogue")).filter(
+            search=SearchQuery(
+                Lexeme("shall") & Lexeme("use") & Lexeme("larger") | Lexeme("nostrils")
+            )
+        )
+        self.assertCountEqual(searched, [self.bedemir0, self.verse2])
+
+    def test_invert(self):
+        searched = Line.objects.annotate(search=SearchVector("dialogue")).filter(
+            character=self.minstrel, search=SearchQuery(~Lexeme("kneecaps"))
+        )
+        self.assertCountEqual(searched, [self.verse0, self.verse2])
+
+    def test_advanced_invert(self):
+        """
+        Inverting a query that uses a combination of & and |
+        should return the opposite of test_advanced.
+        """
+        searched = Line.objects.annotate(search=SearchVector("dialogue")).filter(
+            search=SearchQuery(
+                ~(
+                    Lexeme("shall") & Lexeme("use") & Lexeme("larger")
+                    | Lexeme("nostrils")
+                )
+            )
+        )
+        expected_result = Line.objects.exclude(
+            id__in=[self.bedemir0.id, self.verse2.id]
+        )
+        self.assertCountEqual(searched, expected_result)
+
+    def test_as_sql(self):
+        query = Line.objects.all().query
+        compiler = query.get_compiler(connection.alias)
+
+        tests = (
+            (Lexeme("a"), ("'a'",)),
+            (Lexeme("a", invert=True), ("!'a'",)),
+            (~Lexeme("a"), ("!'a'",)),
+            (Lexeme("a", prefix=True), ("'a':*",)),
+            (Lexeme("a", weight="D"), ("'a':D",)),
+            (Lexeme("a", invert=True, prefix=True, weight="D"), ("!'a':*D",)),
+            (Lexeme("a") | Lexeme("b") & ~Lexeme("c"), ("('a' | ('b' & !'c'))",)),
+            (
+                ~(Lexeme("a") | Lexeme("b") & ~Lexeme("c")),
+                ("(!'a' & (!'b' | 'c'))",),
+            ),
+        )
+
+        for expression, expected_params in tests:
+            with self.subTest(expression=expression, expected_params=expected_params):
+                _, params = expression.as_sql(compiler, connection)
+                self.assertEqual(params, expected_params)
+
+    def test_quote_lexeme(self):
+        tests = (
+            ("L'amour piqué par une abeille", "'L amour piqué par une abeille'"),
+            ("'starting quote", "'starting quote'"),
+            ("ending quote'", "'ending quote'"),
+            ("double quo''te", "'double quo te'"),
+            ("triple quo'''te", "'triple quo te'"),
+            ("backslash\\", "'backslash'"),
+            ("exclamation!", "'exclamation'"),
+            ("ampers&nd", "'ampers nd'"),
+        )
+        for lexeme, quoted in tests:
+            with self.subTest(lexeme=lexeme):
+                self.assertEqual(quote_lexeme(lexeme), quoted)
+
+    def test_prefix_searching(self):
+        searched = Line.objects.annotate(
+            search=SearchVector("scene__setting", "dialogue"),
+        ).filter(search=SearchQuery(Lexeme("hear", prefix=True)))
+
+        self.assertSequenceEqual(searched, [self.verse2])
+
+    def test_inverse_prefix_searching(self):
+        searched = Line.objects.annotate(
+            search=SearchVector("scene__setting", "dialogue"),
+        ).filter(search=SearchQuery(Lexeme("Robi", prefix=True, invert=True)))
+        self.assertEqual(
+            set(searched),
+            {
+                self.verse2,
+                self.bedemir0,
+                self.bedemir1,
+                self.french,
+                self.crowd,
+                self.witch,
+                self.duck,
+            },
+        )
+
+    def test_lexemes_multiple_and(self):
+        searched = Line.objects.annotate(
+            search=SearchVector("scene__setting", "dialogue"),
+        ).filter(
+            search=SearchQuery(
+                Lexeme("Robi", prefix=True) & Lexeme("Camel", prefix=True)
+            )
+        )
+
+        self.assertSequenceEqual(searched, [self.verse0])
+
+    def test_lexemes_multiple_or(self):
+        searched = Line.objects.annotate(
+            search=SearchVector("scene__setting", "dialogue"),
+        ).filter(
+            search=SearchQuery(
+                Lexeme("kneecap", prefix=True) | Lexeme("afrai", prefix=True)
+            )
+        )
+
+        self.assertSequenceEqual(searched, [self.verse0, self.verse1])
+
+    def test_config_query_explicit(self):
+        searched = Line.objects.annotate(
+            search=SearchVector("scene__setting", "dialogue", config="french"),
+        ).filter(search=SearchQuery(Lexeme("cadeaux"), config="french"))
+
+        self.assertSequenceEqual(searched, [self.french])
+
+    def test_config_query_implicit(self):
+        searched = Line.objects.annotate(
+            search=SearchVector("scene__setting", "dialogue", config="french"),
+        ).filter(search=Lexeme("cadeaux"))
+
+        self.assertSequenceEqual(searched, [self.french])
+
+    def test_config_from_field_explicit(self):
+        searched = Line.objects.annotate(
+            search=SearchVector(
+                "scene__setting", "dialogue", config=F("dialogue_config")
+            ),
+        ).filter(search=SearchQuery(Lexeme("cadeaux"), config=F("dialogue_config")))
+        self.assertSequenceEqual(searched, [self.french])
+
+    def test_config_from_field_implicit(self):
+        searched = Line.objects.annotate(
+            search=SearchVector(
+                "scene__setting", "dialogue", config=F("dialogue_config")
+            ),
+        ).filter(search=Lexeme("cadeaux"))
+        self.assertSequenceEqual(searched, [self.french])
+
+    def test_invalid_combinations(self):
+        msg = "A Lexeme can only be combined with another Lexeme, got NoneType."
+        with self.assertRaisesMessage(TypeError, msg):
+            Line.objects.filter(dialogue__search=None | Lexeme("kneecaps"))
+
+        with self.assertRaisesMessage(TypeError, msg):
+            Line.objects.filter(dialogue__search=None & Lexeme("kneecaps"))
+
+    def test_invalid_weights(self):
+        invalid_weights = ["E", "Drandom", "AB", "C ", 0, "", " ", [1, 2, 3]]
+        for weight in invalid_weights:
+            with self.subTest(weight=weight):
+                with self.assertRaisesMessage(
+                    ValueError,
+                    f"Weight must be one of 'A', 'B', 'C', and 'D', got {weight!r}.",
+                ):
+                    Line.objects.filter(
+                        dialogue__search=Lexeme("kneecaps", weight=weight)
+                    )
+
+    def test_empty(self):
+        with self.assertRaisesMessage(ValueError, "Lexeme value cannot be empty."):
+            Line.objects.annotate(
+                search=SearchVector("scene__setting", "dialogue")
+            ).filter(search=SearchQuery(Lexeme("")))
+
+    def test_non_string_values(self):
+        msg = "Lexeme value must be a string, got NoneType."
+        with self.assertRaisesMessage(TypeError, msg):
+            Line.objects.annotate(
+                search=SearchVector("scene__setting", "dialogue")
+            ).filter(search=SearchQuery(Lexeme(None)))